(50ml)

Medik8 Pretox 20 ®

Injection-Free alternative to Botulinum Toxin treatment

Muscle Relaxant Gel in Liposome Delivery System.

Muscles contract when they receive a neurotransmitter release from a nerve. Like Botulinum Toxin A, Pretox releases the amount of nerve stimulation on the local muscle tissue being targeted but unlike Botulinum Toxin A, Pretox does not paralyse the muscle completely.

Instead it gently and temporarily reduces the strength of specific muscle contractions thus the formulation of new lines and wrinkles in reduced and old lines appear much less prominent - leaving you with smoother younger looking skin.

Directions

Apply twice daily to clean dry skin. Product should be used sparingly on targeted areas, avoiding upper & lower eyelids and lips. Allow to absorb for 3-5 minutes before applying solution-based products, hydrator, sunscreen or make-up.

We endorse the use of sun protection. Pretox 20 may be used as a stand alone treatment.

Advanced Explanation Before you can understand how Pretox works, you need to be familiar with how muscle contractions are stimulated. Remember, it is the attenuation or muting of muscle contraction in the facial muscle groups which allows wrinkles to 'flatten out' and become much less visible. The following is for educational purposes only. hover over the steps 1 - 5 below <

Results & Science

• Pretox® contains an inoffensive hexapeptide composed of natural amino acids
• It is a safe and relatively inexpensive alternative to harsh, muscle paralysis treatment
• Stimulates the skin fibroblasts in order to reconstitute the extracellular matrix
• Leads to the synthesis of collagen I and IV, fibronectine and glycosaminoglycans (GAGs)
• Stimulates wound healing and gene expression, without the pro-inflammatory reactions of other treatments

Showing the forehead before treatment with Pretox 10®	Showing the forehead after 30 days treatment with Pretox 10®
Showing the eye before treatment with Pretox 10®	Showing the eye after 30 days treatment with Pretox 10®

Pretox® vermindert de diepte van de rimpels in het gezicht veroorzaakt door de samentrekking van spieren van gezichtsuitdrukking, met name op het voorhoofd & rond de ogen. Het voorkomt de veroudering van huid veroorzaakt door herhaaldelijke bewegingen van het gelaat als gevolg van buitensporige afgifte van catecholamine . Deze grafiek (links) laat het effect zien dat Pretox heeft op de afgifte van catecholamine, vergeleken met een verwante peptide. Klinische tests hebben aangetoond dat Pretox® het SNARE Complex remt in de verouderende huid. De grafiek toont tests die Pretox 10® vergelijkt met 6 andere merken van peptiden met betrekking tot het percentage van de SNARE Complex-vorming

As is clearly visible, Pretox 10, in a similar way to Botulinum Toxin A, inhibits SNARE complex formation, that is to say muscle contraction to a greater extent than the control and other related peptides. In fact, Pretox 10 is up to 70% more effective at reducing muscle stimulation than others available. Pretox 20 contains DOUBLE the amount of active ingredient than that in Pretox 10 however clinical trials were performed at the 10% concentration, hence the data and images for Pretox 10 being given above